Experimental setup for the ultrasonic fractionation of flowing whole blood in a capillary

Abstract If a long ultrasound driving pulse is chosen such, that its frequency greater than the resonance of one cell type and less another type, cells are separated in different nodes antinodes standing sound field. The purpose this study was to build an experimental setup for ultrasonic fractionation whole blood flow conditions. Blood separation into separate components, commonly used analysis transfusions. comprised container with singleelement transducers customisable elevation azimuth, focussed on capillary through which flowing. acoustic focus coincided optical microscopic system high-speed camera attached. Ultrasound were centre frequencies between 1MHz 20MHz pressure amplitudes 1MPa. duty cycle 10% all experiments. field view 0.2 × 0.2mm2. resolution speed allowed visibility red white during Preliminary results show could be forced move opposite directions. pressures representative those clinical diagnosis. We have shown feasible using ultrasound. Sonic might indicator diseases such as malaria.